The brightest take on this week’s science
Never fear. Scientists are working on a new treatment for panic disorders, using a common antibiotic.
Plus, a world-first transplant: An adult man has regained viable sperm from the tissue of his frozen childhood testicle.
Also in this issue:
👟 Movement can trigger ‘brain cleaning’
🤯 A mind-blowing fact about your nostrils
🔬 A microscope mystery
Let’s get learning!
LOOK OUT
A Common Antibiotic May Help Panic Disorders
A common antibiotic may have what it takes to help treat panic disorders.
Panic attacks are scary, overwhelming experiences that are sometimes treated with a benzodiazepine called clonazepam (usually branded as Klonopin or Rivotril).
New research in mice and humans suggests that this drug may benefit from the presence of another.
Minocycline is an antibiotic that has an anti-inflammatory effect at low doses.
Alongside clonazepam, this drug reduced the intensity of panic attacks among nearly 50 human participants.
In mice, the antibiotic appeared to dampen bursts of microglial activity associated with panic attacks within the brainstem, a region involved in breathing control.
Researchers now hope to conduct larger clinical trials on the antibiotic to see if it can be repurposed.
HEADLINES
This Week in Science
LOOK IN
Movement Can Trigger 'Brain Cleaning'
Getting up and moving the body could potentially kickstart a ‘wash cycle’ in your brain, cleaning your neurological tissue of waste.
Using mouse models and simulations, researchers at Pennsylvania State University have found evidence that movement in the abdomen can send ripples of activity all the way up to the brain.
When mice walked on treadmills, researchers noticed their brains shifted immediately after their abdomens contracted, almost like the effect of a hydraulic pump.
This suggests that if someone is doing crunches, it may push blood from their abdomen all the way to their spinal cord, thereby increasing pressure in the brain.
Penn State researchers liken the brain to a sponge that sometimes gets dirty and needs to be wrung out.
Perhaps exercise is one way to twist out the toxins.
ZOOM ZONE
Microscope Mystery: What Do You See?

(Dennis Kunkel Microscopy/Science Photo Library/Getty Images)
A) Heart capillary
B) Flower seed
C) Dust mite poop
D) Oil gland
Answer at the bottom.
LOW-KEY GENIUS
World First: Sperm Regained From Childhood Testicular Tissue
In a world first, a medical team in Brussels claims to have partially restored a man’s sperm production using his own childhood testicular tissue.
The patient was born with an inherited blood disease called sickle cell anemia, and in childhood, he underwent a course of chemotherapy and radiation.
These treatments can be toxic to the gonads and often leave people infertile, but children do not have mature sperm to freeze for the future.
Before undergoing treatment, the male patient in Brussels elected to have one of his testicles frozen.
Seventeen years later, researchers re-transplanted that tissue back into his remaining testicle.
Several grafts are now producing mature and motile sperm.
WOW FACTOR
Science Fact of The Week

(miniseries/E+/Getty Images)
Your nostrils take turns breathing for you. One side is typically more open than the other. Then, every few hours, the congestion switches sides.
This is called the ‘nasal cycle’, and it helps ensure the sinuses remain slicked up with moisture.
That way, the air you breathe can be warmed and filtered on its way into your lungs.
DOPAMINE HIT
Before You Go…
Patience + sugar = science

(Giphy)
Microscope answer: Heart capillary
This is a tiny blood vessel in the heart, containing a red blood cell. Capillaries are one of the smallest branches of the arterial system, creating a sort of ‘web’ within tissue that allows for the exchange of nutrients and wastes.
That’s all for today… see you next week!
- Carly





